IMPORTANT INFORMATION

  • CFTR.info is an online educational resource on the genetics of cystic fibrosis (CF) and the role of CF transmembrane conductance regulator (CFTR) in normal human physiology as well as in CF.
  • The information contained herein is intended for healthcare professionals working within the European Union (EU).
  • The content of this website has been developed independently by a group of CF healthcare professionals and is for general information purposes only.
  • All of the information about CFTR and CFTR modulators has been obtained from referenced sources and is in the public domain.
  • This website is not intended to promote or advocate a particular course of treatment or any specific drug, whether licensed or unlicensed, nor is it intended to imply or suggest that any drug be used for any purpose other than that which for which it is licensed in the EU.

ABBREVIATED TERMS & CONDITIONS

  • While we endeavour to keep the information up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the website or the information and related graphics, or products and treatments, contained on the website for any purpose. Any reliance you place on such information is therefore strictly at your own risk.
  • In no event will we be liable for any loss or damage including without limitation, indirect or consequential loss or damage, or any loss or damage whatsoever arising from, or in connection with, the use of this website.
  • Through this website you are able to link to other websites which are not under our control. We have no control over the nature, content and availability of those sites. The inclusion of any links does not necessarily imply a recommendation or endorse the views expressed within them.
  • Every effort is made to keep the website up and running smoothly. However, we take no responsibility for, and will not be liable for, the website being temporarily unavailable due to technical issues beyond our control.

Please see the full Terms & Conditions before using this website.

 

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This e-learning portal is intended for healthcare professionals who wish to learn more about how CFTR mutations and CFTR modulators can impact disease prognosis and the management of CF.

Discover more about CFTR genetics and how this relates to the pathophysiology and treatment of cystic fibrosisClick hereAbout CF
Explore established approaches to CF diagnosis, screening and treatmentClick hereClinical management of CF
Learn about clinical trials and explore clinical trials currently in progressClick hereDrug research and development
Explore ways to explain emerging therapies, such as CFTR modulators, to individuals with CF, their carers and familiesClick herePatients' questions
Access a comprehensive library of links and downloads on CF and CFTRClick hereCFTR resource centre

Cystic fibrosis (CF) is one of the most common life-threatening genetic disorders worldwide. At the very centre of this debilitating disease is a defect in the cystic fibrosis transmembrane conductance regulator (CFTR) – a membrane protein that plays an important role in ion exchange and water balance throughout the body. CFTR modulators were recently developed to target and overcome errors in CFTR and in doing so, represent the first disease-modifying treatment for CF.