• is an online educational resource on the genetics of cystic fibrosis (CF) and the role of CF transmembrane conductance regulator (CFTR) in normal human physiology as well as in CF.
  • The information contained herein is intended for healthcare professionals working within the European Union (EU).
  • The content of this website has been developed independently by a group of CF healthcare professionals and is for general information purposes only.
  • All of the information about CFTR and CFTR modulators has been obtained from referenced sources and is in the public domain.
  • This website is not intended to promote or advocate a particular course of treatment or any specific drug, whether licensed or unlicensed, nor is it intended to imply or suggest that any drug be used for any purpose other than that which for which it is licensed in the EU.


  • While we endeavour to keep the information up to date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the website or the information and related graphics, or products and treatments, contained on the website for any purpose. Any reliance you place on such information is therefore strictly at your own risk.
  • In no event will we be liable for any loss or damage including without limitation, indirect or consequential loss or damage, or any loss or damage whatsoever arising from, or in connection with, the use of this website.
  • Through this website you are able to link to other websites which are not under our control. We have no control over the nature, content and availability of those sites. The inclusion of any links does not necessarily imply a recommendation or endorse the views expressed within them.
  • Every effort is made to keep the website up and running smoothly. However, we take no responsibility for, and will not be liable for, the website being temporarily unavailable due to technical issues beyond our control.

Please see the full Terms & Conditions before using this website.


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Home » About this website

About this website is an educational resource aimed at helping healthcare professionals:

Financial support for this project
Funding for this website been provided through an unrestricted educational grant from Vertex Pharmaceuticals Inc.

How was developed
This website has been developed by an Education Steering Group (ESG) chaired by Prof Dr Kris De Boeck. The group comprises CF healthcare professionals who represent a typical CF care team in Western Europe; eg, physicians, nurses, physiotherapists, nutritionists and psychologists. A CF scientist provided additional insight into the underlying genetics and molecular biology of CF.

The ESG made recommendations about the format and content of an impartial educational resource aimed at CF healthcare professionals based in Europe. is the culmination of this international collaboration and is entirely based on general consensus of the ESG. This process was coordinated by Facilitate Ltd which has provided editorial and technical support.

Educational steering group (in alphabetical order)
Margarida Amaral, University of Lisbon, Lisbon, Cystic Fibrosis
Kris De Boeck (Editor-in-Chief), University Hospital Leuven, Leuven, Belgium
Jane Davies, National Heart and Lung Institute, Royal Brompton & Harefield Foundation NHS Trust, London, UK
Nico Derichs, Charité Medical University, Berlin, Germany
Stuart Elborn, Queens University Belfast, Belfast, UK
Silvia Gartner, Vall d’Hebron University Hospital, Barcelona, Spain
Brenda Grogan, St. Vincent’s University Hospital, Dublin, Ireland
Trudy Havermans, University Hospital Leuven, Leuven, Belgium
Dominique Hubert, Hospital Cochin, Paris, France
Charlotte Lacarrière, Hospital Cochin, Paris, France
Ed McKone, St. Vincent’s University Hospital, Dublin, Ireland
Christine Nagel, Charité Medical University, Berlin, Germany
Katherine O’Neill, Queens University Belfast, Belfast, UK
Daniel Peckham, Leeds Teaching Hospital, Leeds, UK